Below are selected references from our lab.
- Zhang Z, Nadeau P, Song W, Donoviel D, Yuan M, Bernstein A, Yankner BA. Presenilins are required for gamma-secretase cleavage of beta-APP and transmembrane cleavage of Notch-1. Nature Cell Biology 2000 Jul;2(7):463-5.
- Xu J, Kao S-Y, Lee FJS, Song W, Jin L-W and Yankner BA (2002) Dopamine-dependent neurotoxicity of alpha-synuclein: A mechanism for selective neurodegeneration in Parkinson’s disease. Nature Medicine 8:600-606.
- Lu T, Pan Y, Kao S-Y, Li C, Kohane I, Chan J and Yankner BA (2004). Gene regulation and DNA damage in the ageing human brain. Nature 429:833-891.
- Xu J Zhong N, Wang H, Elias JE, Kim CY, Woldman I, Pifl C, Gygi SP, Geula C and Yankner BA (2005). The Parkinson’s disease-asssociated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis. Human Molec. Genetics 14:1231-1241.
- Hass MR and Yankner BA (2005). A Gamma-Secretase Independent Mechanism of Signal Transduction by the Amyloid Precursor Protein. J. Biol. Chem. 280(44):36895-904.
- Isaacs AM, Senn DB, Yuan M, Shine JP, Yankner BA. Acceleration of amyloid beta-peptide aggregation by physiological concentrations of calcium. J. Biol. Chem. 2006 Sep 22;281(38):27916-23.
- Yankner BA, Lu T, Loerch P (2007). The Aging Brain. Annu. Rev. Pathol. Mech. Dis. 3:41–66.
To find these and other publications by Bruce Yankner and our lab members, please search Pub Med. |
