Below are selected references from our lab.
- Zhang Z, Nadeau P, Song W, Donoviel D, Yuan M, Bernstein A, Yankner BA. Presenilins are required for gamma-secretase cleavage of beta-APP and transmembrane cleavage of Notch-1. Nature Cell Biology 2000 Jul;2(7):463-5.
- Xu J, Kao S-Y, Lee FJS, Song W, Jin L-W and Yankner BA (2002). Dopamine-dependent neurotoxicity of alpha-synuclein: A mechanism for selective neurodegeneration in Parkinson’s disease. Nature Medicine 8:600-606.
- Lu T, Pan Y, Kao S-Y, Li C, Kohane I, Chan J and Yankner BA (2004). Gene regulation and DNA damage in the ageing human brain. Nature 429:833-891.
- Xu J Zhong N, Wang H, Elias JE, Kim CY, Woldman I, Pifl C, Gygi SP, Geula C and Yankner BA (2005). The Parkinson’s disease-asssociated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis. Human Molec. Genetics 14:1231-1241.
- Hass MR and Yankner BA (2005). A Gamma-Secretase Independent Mechanism of Signal Transduction by the Amyloid Precursor Protein. J. Biol. Chem. 280(44):36895-904.
- Isaacs AM, Senn DB, Yuan M, Shine JP, Yankner BA (2006). Acceleration of amyloid beta-peptide aggregation by physiological concentrations of calcium. J. Biol. Chem. Sep 22;281(38):27916-23.
- Yankner BA, Lu T, Loerch P (2007). The Aging Brain. Annu. Rev. Pathol. Mech. Dis. 3:41–66.
- Loerch PM, Lu T, Dakin KA, Vann JM, Isaacs A, Geula C, Wang J, Pan Y, Gabuzda DH, Li C, Prolla TA, Yankner BA.(2008). Evolution of the aging brain transcriptome and synaptic regulation.
PLoS ONE. Oct 2;3(10):e3329.
*OpenAccess for PLoS ONE article.
To find these and other publications by Bruce Yankner and our lab members, please search Pub Med. |
